VUF-8430
In today's world, VUF-8430 has become a topic of great relevance and interest to a wide spectrum of the population. With the advancement of technology and globalization, VUF-8430 has positioned itself as a relevant element in people's daily lives, impacting everything from the way they communicate to the way they carry out their business transactions. The importance of VUF-8430 has transcended borders and has become a topic of debate in different areas, generating conflicting opinions and putting on the table the need to reflect on its implications in today's society. In this article, we will explore different perspectives and studies on VUF-8430, in order to understand its impact and relevance today.
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| Names | |
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| Preferred IUPAC name
2-ethyl carbamimidothioic acid ester[citation needed] | |
| Identifiers | |
3D model (JSmol)
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| Abbreviations | VUF-8430 |
| ChEMBL | |
| ChemSpider | |
PubChem CID
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| UNII | |
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| Properties | |
| C4H11N5S | |
| Molar mass | 161.23 g·mol−1 |
| log P | -1.367 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
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VUF-8430 is a histamine agonist selective for the H4 subtype.
References
- ^ Smith FM, Haskelberg H, Tracey DJ, Moalem-Taylor G (2007). "Role of histamine H3 and H4 receptors in mechanical hyperalgesia following peripheral nerve injury". Neuroimmunomodulation. 14 (6): 317–25. doi:10.1159/000125048. PMID 18401194. S2CID 23020760.
- ^ Lim, HD; Smits, RA; Bakker, RA; Van Dam, CM; De Esch, IJ; Leurs, R (2006). "Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist". Journal of Medicinal Chemistry. 49 (23): 6650–1. doi:10.1021/jm060880d. PMID 17154494.
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