Clobenpropit
In this article, we will explore in detail the topic of Clobenpropit, which has captured the attention and interest of many people in recent years. We will delve into its origins, its current relevance and its impact in different areas of daily life. We will also analyze the various perspectives and opinions that exist around Clobenpropit, in order to provide our readers with a complete and balanced view. Through this article, we hope to offer a deeper and richer understanding of Clobenpropit, as well as encourage debate and reflection around this fascinating topic.
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| Formula | C14H17ClN4S |
| Molar mass | 308.83 g·mol−1 |
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Clobenpropit is a histamine H3 receptor antagonist. It has neuroprotective effects via stimulation of GABA release in brain cells in vitro.
References
- ^ Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P (2007). "The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes". European Journal of Pharmacology. 567 (3): 206–210. doi:10.1016/j.ejphar.2007.04.032. PMID 17537431.
- ^ Dai H, Fu Q, Shen Y, Hu W, Zhang Z, Timmerman H, Leurs R, Chen Z (2007). "The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons". European Journal of Pharmacology. 563 (1–3): 117–123. doi:10.1016/j.ejphar.2007.01.069. PMID 17350613.
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