The issue of Self-incrimination clause is widely discussed today as it affects a large number of people around the world. Since its discovery, Self-incrimination clause has sparked growing interest in the scientific community, as well as society in general. Over the years, numerous studies and research have been carried out that seek to fully understand the implications and consequences of Self-incrimination clause in terms of health, society and the environment. In this article, different aspects related to Self-incrimination clause will be examined, providing an overview of its importance and impact today.