Fibrinoid necrosis

In this article we will explore the impact of Fibrinoid necrosis on today's society. Over the years, Fibrinoid necrosis has played a crucial role in various aspects of daily life, generating widespread debate and divided opinion. Since arriving on the world stage, Fibrinoid necrosis has captured the attention of millions of people and left an indelible mark on history. Through detailed and comprehensive analysis, we will examine how Fibrinoid necrosis has shaped our social interactions, influenced our decisions, and guided the course of society at large. Additionally, we will explore the future implications of Fibrinoid necrosis and its role in the evolution of humanity.

Irreversible, uncontrolled cell death

Fibrinoid necrosis is a specific pattern of irreversible, uncontrolled cell death that occurs when antigen-antibody complexes are deposited in the walls of blood vessels along with fibrin. It is common in the immune-mediated vasculitides which are a result of type III hypersensitivity. When stained with hematoxylin and eosin, they appear brightly eosinophilic and smudged.

Diseases

Fibrinoid necrosis is not limited to the immune-mediated vasculitides; many pathologic processes can lead to areas of fibrinoid necrosis. In systemic lupus erythematosus, the dermis is often affected by fluid accumulation and inflammation around the small vessels in the skin, which may show prominent fibrinoid necrosis. Also it's seen in rheumatoid nodules with similar pathology. Also seen in Serum Sickness(Type III hypersensitivity reaction)

References

1. ^ ^{a b} Robbins and Cotran pathologic basis of disease. Kumar, Vinay, Abbas, Abul K., Aster, Jon C., Perkins, James A. (Ninth ed.). Philadelphia, PA. 2014. ISBN 9781455726134. OCLC 879416939.{{cite book}}: CS1 maint: location missing publisher (link) CS1 maint: others (link)

This article related to pathology is a stub. You can help Wikipedia by expanding it.

• v
• t
• e